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Letters to the Editor

Indian Pediatrics 1999; 36:615-616

Spectrum of C olonic Polyps


We read with interest the recent study on "Spectrum of colonic polyps". Authors have reemphasized the notion that the majority of colonic polyps in children are solitary and rectosigmoid in location. But the method used for preparing a child for colonoscopy is controversial. For oral electrolyte lavage solution containing polyethylerie glycol (PEG), there is no need to keep the child on liquid diet for one day and to give enema a day before. Moreover using PEG a night before will cause great inconvenience to the child and also to. the parents because of frequent motions. It has been recommended(2) that on the day of the procedure (4 hours before colonoscopy) PEG should be used. PEG containing lavage solution is isotonic and isoosmolar to the plasma when reconstituted (1 packet in 2 liters of water)(2) and thereby it prevents water-electrolyte absorption/secretion. However, authors (1) have prepared the PEG solution in 500 to 1000 ml of water, which was obviously hypertonic and hyperosmolar with an increased risk of water- electrolyte imbalance to a small child. Most people even in India(3) now use ketamine, not general anesthesia for sedation during endoscopy in pediatric cases. It is safe and does not require any extensive monitoring system. But in this study(l) general anesthe- sia was used in the majority of cases. In our experience(4) of 236 children with colonic polyp, 93% were juvenile polyp, 76% solitary and 85% were in the rectosigmoid region. Corresponding figures in this sereis(l) are 75%, 80% and 90%. Interestingly, we have seen(5) 17 cases of juvenile polyposis (>5 juvenile polyps) but the present series(l) does not have any such case. Adenomatous changes in a juvenile polyp, which we have documented in 59% cases of juvenile polyposis(5), sometimes completely replace juvenile polyp(6). In such cases, if all polyps are nor-examined carefully a misdiagnosis of adenomatous polyposis, (which, is otherwise rare in India) may be made instead of juvenile polyposis. Authors have mentioned that a single juvenile polyp has no malignant potential and has to be removed only if symptomatic. This is not true. There are reports(7,8) of adenomatous changes and colorectal malignancy in solitary juvenile polyp with adenotnatous changes. Therefore, solitary juvenile polyp carries a small but definite neoplastic potential and needs to be removed even if asymptomatic.



Vinal Poddar,
B.R. Thapa,

Division of Pediatric Gastroenterology, Department of Gastroenterlogy,
Post Graduate Institute of Medical
Education and Research,
Chandigarh 160 012, India.
E-mail: [email protected]
 

References

1. Gopanpallikar AM, Sawant P, Rathi P, Chodankar CM, Bhatnagar M, Nanivadekar SA. Spectrum of colonic polyps. Indian Pediatr 1998; 35: 897-900.

2. Diploma JA, Brady CE, Stewart DL, Karling DA, McKinney MK, Clement OJ, et at. Comparison of colon cleansing methods in preparation for colonoscopy. Gastroenterology 1984; 86: 856-860.

3. Aggarwal A, Ganguly S, Anand VK, Patwari AK. Efficacy and safety of intravenous ketamine for sedation and analgesia during pediatric endoscopic procedures. Indian Pediatr 1998; 35: 1211-1214.

4. Poddar D, Thapa BR, Vaiphei K, Singh K. Colonic polyps: Experience of 236 Indian children. Am J Gastroenterol 1998; 93: 619- 612.

5. Poddar D, Thapa BR, Vaiphei K, Rao KLN, Mitra SK, Singh K. Juvenile polyposis in a tropical country. Arch Dis Child 1998; 78: 264-266.

6. Goodman ZD, Yardley JH, Milligan FD. Pathogenesis of colonic polyps in multiple juvenile polypsis. Report of care associated with gastric polyps and carcinpma of the rectum. Cancer 1979;43: 1906-1913.

7. Giardiello FM, Hamilton SR, Kern SE, Offerhaus GJA, Green PA, Celano P, et at. Colorectal neoplasia in juvenile polyposis or juvenile polyps. Arch Dis Child 1991; 66: 971- 975.

8. Scilla FW. Carcinoma in a rectal polyp. Am J Surg 1954; 4: 434-439.

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