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Letters to the Editor

Indian Pediatrics 2004; 41:1173-1174

Perforative Duodenal Tuberculosis


A six-year-old female presented with severe abdominal pain and bilious vomiting since 6 hours. For the last 6 months she was being treated with antihelminthics, anti-spasmodics and antacids for intermittent/colicky abdominal pain.

Examination showed a cachexic, pale child with tachycardia and tachypnea. Abdomen was mildly distended with no visible loops. Palpation revealed tenderness and guarding in upper abdomen. Liver and spleen were not palpable. Per rectal examination showed bogginess.

Investigations showed hemoglobin of 7.8 g/dL Erythrocyte sedimentation rate was 31 mm/hr. All other serum investigations were within normal limits. X-ray abdomen showed massive gas under diaphragm. X-ray chest was normal. Ultrasonography showed free fluid in Morrisons and Douglas pouch.

Fig. 1. Stricture in the terminal part of duodenum with tubercles (marked with two arrows) and a perforated ulcer. (marked with one arrow) and dueodenum marked with black single arrow.

Exploration revealed a stricture in the terminal part of duodenum, tubercles and a (Fig. 1) perforated ulcer proximal to the stricture. Mesenteric lymph nodes were enlarged and appeared caseating. Rest of the viscera were normal. The perforation was closed in two layers and omentopexy was done. Side to side duodeno-jejunostomy followed, for non-passable stricture. Mesenteric lymph nodes were biopsied. Histopathology confirmed tuberculosis. Antitubercular treatment was initiated. Postoperative course was uneventful.

Tuberculosis of stomach and duodenum is rare(1) even in patients with pulmonary tuberculosis. Duodenal perforation proximal to tubercular stricture is exceptional. Extreme variety of gastric and duodenal tuberculosis is attributed to factors like sparsity of lymphoid structures, intact mucosa, rapid passage of ingested organisms and acidity of the stomach.

The possible routes of infection are directly through mucosa, hematogenous, lymphatic and from adjacent structures in continuity(2) through serosa. Extensive lymphadenopathy is common. The above two reasons make our case more rare.

The treatment of gastric and duodenal tuberculosis is primarily medical with anti-tuberculosis drugs(3). Surgery is indicated in cases with obstruction or perforation of an ulcer.

Paras R Kothari,
Bharati Kulkarni,

Department of Pediatric Surgery,
L.T.M. Medical College and
General Hospital,
Sion, Mumbai 400 022, India.
E-mail: [email protected]

References

 1. Agrawal S, Shetty SV, Bakshi G. Primary hypertrophic tuberculosis of pyloroduodenal area: Report of 2 cases. J Postgrad Med 1999; 45: 10-12.

2. Balikian JP, Yenikornshian SM, Jidejian YD. Tuberculosis of pyloro-duodenal area. Am J Roentgenol 1987; 101: 414-420.

3. Yeomans ND, Lambert JR. Infections of the Stomach and Duodenum. Gasteroenterology. 5th edition. Vol 1. Philadelphia: WB Saunders Company; 1995 p 808-809.

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