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Indian Pediatr 2019;56: 429 |
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Vitamin D Supplementation: Do Indian Children Need Higher
Dose?: Author's Reply
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Raman Kumar Marwaha
Scientific Advisor (Projects), International Life
Science Institute (India).
Email:
[email protected]
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We thank the authors for their interest in our study, and appreciate
this opportunity to reply to their comments. In our study of
pre-pubertal girls, we found that a daily dose of 1000 vitamin D3
achieved and maintained vitamin D sufficiency in 97% of girls [1]. In
Table I, we mentioned mean and standard deviation values of baseline
hormonal and biochemical parameters. Table II showed changes in hormonal
and biochemical parameters after vitamin D3 supplementation. All P
values were based on non-parametric one-way analysis of variance
(DUNN test). We used non-parametric DUNN test in view of large standard
deviations in the values. We agree with the limitation of study that the
results may not be applicable to children of both sexes, in all age
groups, lower socioeconomic strata, and throughout the year. Further
studies with larger sample size and longer follow-up are required to
confirm our findings and to evaluate the long-term benefit of the
vitamin D supplementation.
References
1. Marwaha RK, Mithal A, Bhari N, Sethuraman G, Gupta S, Shukla M,
et al. Supplementation with three different daily doses of vitamin
D3 in healthy pre-pubertal school girls: A cluster randomized trial.
Indian Pediatr. 2018;55:951-6.
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