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Correspondence

Indian Pediatr 2019;56: 429

Vitamin D Supplementation: Do Indian Children Need Higher Dose?: Author's Reply

 

Raman Kumar Marwaha

Scientific Advisor (Projects), International Life Science Institute (India).

Email: [email protected]

 

 


We thank the authors for their interest in our study, and appreciate this opportunity to reply to their comments. In our study of pre-pubertal girls, we found that a daily dose of 1000 vitamin D3 achieved and maintained vitamin D sufficiency in 97% of girls [1]. In Table I, we mentioned mean and standard deviation values of baseline hormonal and biochemical parameters. Table II showed changes in hormonal and biochemical parameters after vitamin D3 supplementation. All P values were based on non-parametric one-way analysis of variance (DUNN test). We used non-parametric DUNN test in view of large standard deviations in the values. We agree with the limitation of study that the results may not be applicable to children of both sexes, in all age groups, lower socioeconomic strata, and throughout the year. Further studies with larger sample size and longer follow-up are required to confirm our findings and to evaluate the long-term benefit of the vitamin D supplementation.

References

1. Marwaha RK, Mithal A, Bhari N, Sethuraman G, Gupta S, Shukla M, et al. Supplementation with three different daily doses of vitamin D3 in healthy pre-pubertal school girls: A cluster randomized trial. Indian Pediatr. 2018;55:951-6.


 

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