1. The study [1] was done between August 2013 and
July 2014 when the Endocrine Society Clinical Practice guidelines
published in 2011 was the most recent one available. Subsequent
publications also suggest that though for the skeletal effects, a
serum 25 (OH) Vitamin D level of 20 ng/mL is sufficient, for the
non-skeletal benefits the optimum level may be higher [2]. The
guidelines referred to in the letter by the reader were all
published after our study was over.
2. The original manuscript had the P
values in the table, which were deleted during editing. The odds
ratio (95% CI) for partial or poor control of asthma in the vitamin
D deficient group as compared to the sufficient/ insufficient group
was 58.5 (9.7, 354.1) with P <0.001.
3. It was a period sample as mentioned in the
methodology.
4. The objectives were to study the association
between asthma control and serum 25 (OH) Vitamin D levels.
Regardless of whether the child was on supplements or not, we wanted
to see if low serum level was associated with suboptimal control.
5. Our study enrolled only those with good
compliance and technique as mentioned in the methodology, and the
comorbidities were also noted. Though more children in whom asthma
was not well-controlled had allergic rhinitis (68% vs 41%),
the difference was not statistically significant (P >0.05).
6. Though recommended, pulmonary function test is
not being done routinely in our pediatric asthma patients.