Home            Past Issues            About IP            About IAP           Author Information            Subscription            Advertisement              Search  

   
Correspondence

Indian Pediatr 2019;56: 252-253

Association Between Vitamin D and Asthma Control: Does it Really Exist?: Author's Reply

 

Padmasani Venkat Ramanan

Department of Pediatrics, Sri Ramachandra Medical College and Research Institute, Chennai, India.
Email: [email protected]

 

 

1. The study [1] was done between August 2013 and July 2014 when the Endocrine Society Clinical Practice guidelines published in 2011 was the most recent one available. Subsequent publications also suggest that though for the skeletal effects, a serum 25 (OH) Vitamin D level of 20 ng/mL is sufficient, for the non-skeletal benefits the optimum level may be higher [2]. The guidelines referred to in the letter by the reader were all published after our study was over.

2. The original manuscript had the P values in the table, which were deleted during editing. The odds ratio (95% CI) for partial or poor control of asthma in the vitamin D deficient group as compared to the sufficient/ insufficient group was 58.5 (9.7, 354.1) with P <0.001.

3. It was a period sample as mentioned in the methodology.

4. The objectives were to study the association between asthma control and serum 25 (OH) Vitamin D levels. Regardless of whether the child was on supplements or not, we wanted to see if low serum level was associated with suboptimal control.

5. Our study enrolled only those with good compliance and technique as mentioned in the methodology, and the comorbidities were also noted. Though more children in whom asthma was not well-controlled had allergic rhinitis (68% vs 41%), the difference was not statistically significant (P >0.05).

6. Though recommended, pulmonary function test is not being done routinely in our pediatric asthma patients.

References

1. Kaaviyaa AT, Krishna V, Arunprasath TS, Ramanan PV. Vitamin D deficiency as a factor influencing asthma control in children. Indian Pediatr. 2018;55:969-71.

2. Bouillon R, Van Schoor NM, Gielen E, Boonen S, Mathieu C, Vanderschueren D, et al. Optimal Vitamin D Status: A Critical Analysis on the Basis of Evidence-Based Medicine. J Clin Endocrinol Metab, 2013;98: E1283-304.


 

Copyright © 1999-2019 Indian Pediatrics