|
Indian Pediatr 2015;52: 77 |
|
Re-emergence of Swine flu in Central India,
2014
|
Vipin M Vashishtha
Consultant Pediatrician, Mangla Hospital and Research
Center, Shakti Chowk, Bijnor, UP, India.
Email: [email protected]
|
A 38-year-old, HIV-negative male plumber with no history of travel and
no underlying illness succumbed to pneumonia as a complication of Swine
flu in a private hospital in urban Nagpur, India in mid-September 2014.
He had high fever and respiratory distress culminating into respiratory
failure. He is one of the first few mortalities this season from the
Orthomyxovirus Influenza A-H1N1, having human-to-human transmission by
air-borne route and fomites [1]. His two male children, 7 and 9
years, presented to us with complaints of low grade fever,
non-productive cough, stuffy nose and anorexia for 10-15 days. Sore
throat, respiratory distress, cyanosis, rash, bleeding or other systemic
manifestations were not reported. Both the children tested positive for
Swine flu by Reverse Transcriptase Real Time-Polymerase Chain Reaction
run on throat swab as per standard protocol from Centres for Disease
Control and Prevention, US [2]. They received oral Oseltamivir 3
mg/kg/dose twice daily on ambulatory basis for 5 days, and kept under
close telephonic follow-up.
Several adults and children in the extended family
were exposed to the cases during their illness and during the rituals
that follow death, which include congregation and communal dining which
can amount to exposure to aerosols and fomites. Many individuals exposed
in the family subsequently developed symptoms suggestive of swine flu
and were successfully managed as per Clinical management protocol [3].
The case report is from Maharashtra, the state which
had reported the maximum mortality from India in the 2009-10 pandemic
amongst laboratory confirmed cases of Swine flu [4]. After the 2009-10
pandemic, the virus has been declared as a human seasonal flu
virus. Since 2009, a significant number of patients are being reported
in 2014 for the first time pointing towards resurgence. The drug
Oseltamivir is to be administered orally within 48 hours of falling sick
for best results [3]. Delay in diagnosis and lack of availability of
drug in public sector can contribute to the adverse outcome. Public
health measures need to be taken to increase awareness regarding
preventing contact with the infected cases, especially during
care-taking activities [3] and after death of an individual. Widespread
vaccination of at-risk individuals with the tailor-made vaccine is an
important mitigation strategy to curb the outbreaks [5].
References
1. 2009 H1N1 Flu and You. CDC Jan 13 2010. Available
from: http://www.cdc.gov/flu/freeresources/2009-10/pdf/h1n1andyou.pdf.
Accessed September 19, 2014.
2. WHO. CDC Protocol of Real Time RTPCR for influenza
A (H1N1). Geneva: World Health Organization, 2009. Available from:
http://www.who.int/csr/resources/publica tions/swineflu/CDCRealtimeRTPCR_
SwineH1Assay-2009_20090428.pdf. Accessed September 19, 2014.
3. Directorate General of Health Services, Ministry
of Health and Family Welfare, Government of India. Clinical Management
Protocol and Infection Control Guidelines. Available from:
http://www.mohfw-h1n1.nic.in/documents/pdf/5.%20Clinical%20Management%20Protocol-Pandemic%20influenza%20A%20H1N1.pdf.
Accessed September 10, 2014.
4. Office of the Director, Emergency Medical Relief,
Directorate General of Health Services, Government of India. Weekly data
of Influenza A H1N1 (for the week ending 12th December 2010) and
cumulative number of Lab confirmed cases and deaths- state wise.
Available from:
http://www.mohfw-h1n1.nic.in/documents/PDF/SituationalUpdatesArchives/december2010/Situational
%20Updates%20on%2012.12.2010.pdf. Accessed September 17, 2014.
5. Ministry of Health and Family Welfare, Directorate
General of Health Services, (Emergency Medical Relief). Guidance on
pandemic vaccination. Available from:
http://www.mohfw-h1n1.nic.in/vaccine.html. Accessed September 15,
2014.
|
|
|
|