Letters to the Editor Indian Pediatrics 2006; 43:77-78 |
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Lipoblastoma in Infancy |
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Lipoblastoma is a relatively rare tumor that occurs in infancy and early childhood and arises from embryonic white fat. The most common symptom is a painless mass with or without increasing size. The trunk, extremities, head and neck, retroperitoneum, inguinal canal, peritoneal cavity, and lung are the common tumor sites. Histopathologic examination shows a cellular neoplasm composed of immature adipocytes with relatively well-defined septa, frequent lipoblasts and a fine vascular network. Lipoblastomas are circumscribed while lipoblastomatosis is diffuse and infiltrative. It is important to completely excise the tumor to avoid leaving residual tumor and to prevent recurrences which mostly occur within 2 years. Confusion with myxoid liposarcoma, well-differentiated liposarcoma, and typical lipomas may occur. Anup Mohta, |