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Correspondence

Indian Pediatrics 2007; 44:939

Diagnosis of Enteric Fever in Children: Importance of Relative Granulocytosis


I read with interest the report by Kundu, et al., on diagnosis of enteric fever in children (1). It has been stated that complete blood count in enteric fever is unremarkable and the white blood cell count is normal in most cases and leukocytosis makes the diagnosis less probable. However, it has not been mentioned whether there is a help of relative granulocytosis in the diagnosis of enteric fever or not. Caglar, et al. had reported relative granulocytosis among children with enteric fever(2). Even though relative granulocytosis in children <2 years of age with enteric fever has already been mentioned before(3), all of their patients were older than 3.5 years old, and granulocytosis did not vary, whether the patients were older or younger than 10 years, and leukopenia was present in only half of patients. It was more marked in children who were sick for less than a week. Therefore, in the presence of relative granulocytosis with leukopenia in children with high fever of undetermined origin, enteric fever should be considered.

M K Caglar,
F S Altuga,

Gaziosmanpasa University,
Faculty of Medicine,
Department of Pediatrics, Tokat, Turkey.
E-mail: [email protected]  

REFERENCES

1. Kundu R, Ganguly N, Ghosh T Kr, Yewale VN, Shah RC, Shah NK. lAP Task Force Report: Diagnosis of enteric fever in children 875. Indian Pediatr 2006; 43: 875-883.

2. Caglar MK, Ozsoylu S, Kama G. Relative granulocytosis in childhood typhoid fever. J Pediatr 1983; 102: 603-604.

3. Krugman S, Katz SL. Salmonella infections, including typhoid fever. In: Krugman S, Katz SL, eds. Infectious Diseases of Children. 7th edn. St Louis: CV Mosby. 1981; p.332.

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