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Correspondence

Indian Pediatr 2019;56: 695-696

Periviable Birth – The Ethical Conundrum: Few concerns

 

Tapas Bandyopadhyay and Arti Maria*

Department of Neonatology, PGIMER and Dr RML Hospital, New Delhi, India.

Email: * [email protected]

 


The article by Nimbalkar and Bansal [1], published recently in Indian Pediatrics, must have caught attention of many clinicians. We were looking forward to discussions around real time delivery room dilemmas in day-to-day life as well as some operational working algorithms/flowcharts that would help making decisions easier in such difficult situations. Through this communication, we have tried to complement the content in this article. Nevertheless, we agree with the author that there is an imminent need to collect our own outcome data in extreme preterm infants to enable framing national guidelines for management of periviable babies.

1. In the section on "The Ethics of Decision-making in the Delivery Room" authors have made a generic discussion around the principles of ethics rather than some practical ethical dilemmas faced by a clinician in a delivery room.

2. At the outset, it may have been good to define a ‘live birth’, What are ‘signs of life’, what constitutes providing either ‘full life support’ or ‘comfort care’ etc. While the Neonatal Resuscitation Program (NRP) guidelines mention first examination of ‘Heart Rate’ after the end of initial steps, do we really examine heart first when dealing with difficult situations of periviability to assess signs of life?

3. Authors have majorly (and infact theoretically rightly so) used gestational age (GA) cut-offs as the main guiding criteria that dictate decisions and actions in tricky situations around periviability. But surely such utopian situations are not invariable. GA is often not known. Hence, a broad framework based on weight cut-offs (which is reliably obtained in all cases at birth) may be more useful and desirable for guiding decisions initiating resuscitation or continuing life support. Another not so uncommon situation is an unbooked pregnant woman who comes and delivers a periviable extreme preterm who needs immediate resuscitation before an informed consent can be obtained.

4. Translating available literature [2] to operational guidelines in our Indian context, we propose the following algorithm:

Ideal situation when GA is known and a timely consent can be obtained: Obtain informed consent in all cases at the limits of viability before initiating resuscitation as well providing life sustaining intervention.

For 22-25 weeks gestation: obtain informed consent before providing full armamentarium of life-sustaining interventions.

When either GA is not precisely known or there may be no time to obtain consent: (i) Initiate resuscitation in all babies weighing ³500 g (10th centile as per Fenton’s chart [3]) and/or born after 22 completed weeks of gestation; (ii) for babies born between 500-600 g, full armamentarium of life- sustaining interventions should be provided till informed consent is obtained; and (iii) provide full armamentarium of life-sustaining interventions in all babies at ³25 weeks’ GA and/or ³600 g (10th centile as per Fenton’s chart [3]) of birth weight.

5. In Table I in 3rd row, 2nd column; i.e. "provide treatment unless provider declines to do so" is probably not justified as ethical principles do not allow the provider to decline treatment particularly when parents prefer to accept treatment.

References

1. Nimbalkar SM, Bansal SC. Periviable birth – The ethical conundrum. Indian Pediatr. 2019;56:13-7.

2. Lee ACC, Katz J, Blencowe H, Cousens S, Kozuki N, Vogel JP, et al. National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010. Lancet Glob Health. 2013;1:e26-e36.

3. Fenton TR, Kim JH. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatr. 2013;13:59.

 

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