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Indian Pediatr 2015;52: 655-656 |
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Monsoon Maladies
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S Sachidananda Kamath
National President, Indian Academy of Pediatrics,
2015.
Email: [email protected]
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The advent of monsoon in India provides a welcome
relief from the dry hot summer and brings waves of life to parched
landscapes across the country, but the cooling showers also bring along
a lot of diseases. Infectious diseases like Dengue fever, Chikungunya,
Hantaviruses, Nipah virus, Chandipura virus, Malaria and the novel H 1N1
influenza virus had emerged or re-emerged as major public health
problems through the last decade in India. Bacterial disease like
Plague, Leptospirosis, Anthrax, Brucellosis, Enterohemorrhagic E.
Coli, Salmonella, Shigella and Staphylococci also remain a threat
during this season [1,2].
Mortality due to infectious diseases has fallen
drastically over the years as a result of sanitation development,
vaccines, antibiotics and other advances in social environment and
medical sciences. However, population growth, urbanization,
environmental pollution, climate change and movement of populations have
been associated with a shift in geographical distribution and
accelerated diffusion of old and new pathogens resulting in an increased
number of outbreaks. Overcrowding, poor sanitation and water supply,
poverty, breakdown of public health measures, changing ecosystems, human
demographics and behavior, microbial adaptation and change, and
international travel and trade also amplify transmission of infectious
diseases [3-6].
Incidence of dengue has increased many folds in the
last decade. Urbanization is strongly associated with its re-emergence.
As the Aedes mosquitoes prefer artificial water containers as its
larval habitat, human habitations became its choice. The four strains of
dengue virus are circulating with an epidemic potential and becoming
endemic and hyper-endemic in many regions [5]. Build-up of a
susceptible, non-immune population in India due to the absence of
circulation of the virus for decades led to the resurgence of
Chikungunya infection from Southern and Central parts of the country
since 2006. Although deaths are not common, the morbidity and disability
caused due to Chikungunya is enormous [5].
The novel H1N1
virus, reported first in the country in 2009 from Hyderabad,
subsequently spread rapidly throughout India, and is still in
circulation, even causing deaths [3,7]. Crimean-Congo haemorrhagic fever
(CCHF) outbreak was reported in Gujarat in 2011. These outbreaks were
zoonotic, and caused a person-to-person spread in hospital setting. High
index of clinical suspicion, early laboratory diagnosis and institution
of containment measures curtailed further spread of the disease [6].
Acute encephalitis syndrome (AES) takes a heavy toll in a few States of
India, in children below the age of 10 years. During the past five
decades, the incidence of AES in the country has been on the rise [8,9].
With mosquitoes (Culex species) as the principal vectors along with a
bird-mosquito natural cycle, the role of ardeid birds in the maintenance
of Japanese encephalitis virus and West Nile virus has been described in
India [5]. The Nipah virus was responsible for outbreaks in Siliguri,
West Bengal in 2010 with a case fatality rate of 74%. Due to the
abundant presence of natural reservoir Pteropus bats (fruit bats) in the
North-Eastern parts of India, there is still an outbreak potential [5].
Chandipura virus, transmitted by bite of the female sandfly, was
reported from Andhra Pradesh in 2003 and Gujarat in 2004, and is
considered a potentially dangerous emerging virus [5]. Recent
data also suggest the presence of Hantavirus infections in India.
Kyasanur Forest Disease virus is maintained as enzootic in small mammals
and monkeys in the forests in Southern India [5]. Recent reports suggest
continuing presence of Rickettsial diseases in India as well [10]. The
reported numbers are underestimates as there are no community-based
studies, and there is a lack of availability of confirmatory laboratory
tests.
Emerging infectious diseases affect the credibility
of health services, and threaten economic development. A strategic
vision and an effective plan of action are needed to combat these
threats. We need a strong public health structure, effective risk
communication, an efficient surveillance system, strong laboratory
networks, epidemic preparedness and rapid response. Current surveillance
systems are not sufficient to adequately address the problem of emerging
diseases.
Research efforts to develop more effective and
advanced tools to combat the resurgence of the diseases are important.
Diagnostic tools, and treatment and prevention facilities need to be
developed; laboratories for testing need to be upgraded and maintained.
A close interaction and bonding between the research community and the
public health, agriculture and animal husbandry are crucial to combat
the menace of these diseases.
References
1. Khanna M, Kumar P, Choudhary K, Kumar B, Vijayan
VK. Emerging influenza virus: A global threat. J Biosci. 2008;33:475-82.
2. Chugh TD. Emerging and re-emerging bacterial
diseases in India. J. Biosci. 2008;33:549-55.
3. Committee on Emerging Microbial Threats to Health
in 21st Century 2003 Microbial threats to health in the United States:
Emergence, defection and response (eds) M S Smolinski, M A Hamburg and J
Leaderberg (Washington DC: National Academy Press)
4. Dash AP, Bhatia R, Sunyoto T, Mourya DT. Emerging
and re-emerging arboviral diseases in Southeast Asia. J Vector Borne
Dis. 2013;50:77-84.
5. Woolhouse ME, Gowtage-Sequeria S. Host range and
emerging and reemerging pathogens. Emerg Infect Dis. 2005;11:1842-7.
6. Kant L. Combating emerging infectious diseases in
India: Orchestrating a symphony. J Biosci. 2008;33:425-7.
7. Dhande L, Khairnar K. Re-emergence of Swine flu in
Central India, 2014. Indian Pediatr. 2015;52:77.
8. Yewale VN. Misery of mystery of Muzaffarpur.
Indian Pediatr. 2014;51:605-6.
9. John TJ. Encephalopathy clusters conflated with
encephalitis outbreaks. Indian Pediatr. 2014;51:937.
10. Sankhyan N, Saptharishi LG, Sasidaran K, Kanga A, Singhi SC.
Clinical profile of scrub typhus in children and its association with
hemophagocytic lymphohistiocytosis. Indian Pediatr. 2014;51:651-3.
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