We have a few comments on the recent article by Saini, et al. .
The attempt to investigate the shortest possible duration of antibiotics
in probable neonatal sepsis is appreciable as it will lead to decreased
economic burden, hospital stay, and adverse effects associated with
The Table II showing comparison of co-interventions,
number of neonates receiving CPAP and number receiving conventional oxygen
shows statistically significant difference in the two groups . More
invasive procedure can lead to more chances of introduction of fresh
sepsis in otherwise culture negative non sepsis children. This could be
one of the reasons behind more cases presenting with treatment failure in
the group receiving antibiotics for 7 days as more number of children in
this group incidentally received CPAP.
The basis of choosing fifteen days as cut off time for
following up neonates after completion of antibiotics has not been
Sunny Narang and Vipul Gupta
MMIMSR, Mullana, Ambala.