|
Indian Pediatr 2014;51: 319 |
 |
Mosquito Repellent Vaporizer Poisoning – Is
the culprit Transfluthrin or Kerosene?
|
Sudha Chandelia and Nand Kishore Dubey
Department of Pediatrics, PGIMER and associated Dr RML
Hospital, New Delhi, India.
Email:
[email protected]
|
A 3-year-old boy presented with complaints of sudden onset
vomiting and difficult breathing following accidental
ingestion of a liquid mosquito repellent vaporizer (LMRV).
He was alert, respiratory rate was 54/min, and there were
subcostal, intercostal retractions, nasal flaring, and fine
crepitations over right lower chest. Arterial blood gas was
normal on 6 L/min of inhaled oxygen. Chest radiograph done
after 6 hours, showed pneumonitis in right middle and lower
zones. He improved over 48 hours without antibiotics.
The use of LMRV is common in setting of
infections like malaria and dengue. These products contain
derivatives of pyrethrins as mosquito repellent and kerosene
as the solvent. Pyrethrins have poor dermal absorption and
rapid metabolism. Popular brands use 0.88% of the chemical,
that was transfluthrin in the present case. Toxicity results
mainly in central nervous system (CNS) symptoms like
headached, dizziness, drowsiness, status epilepticus and
respiratory failure. These chemicals act by prolonging the
opening of sodium channels leading to increased influx of
sodium ions and thus hyper-excitation of the nervous system
[1]. Cardiac dysfunction has also been described, but lung
injury is not commonly reported [2,3].
The poisoning of the second component of
LMRV –kerosene – is well recognized. Being highly volatile
and less viscous, it can cause life threatening lung injury
in the form of aspiration pneumonitis and ARDS. Chest
radiograph may be normal initially and abnormalities like
fine perihilar opacities, basilar infiltrates, and
atelectasis may appear after some hours of ingestion. The
use of LMRV increases the risk of kerosene poisoning even in
setting where it is not used as fuel. We emphasize that LMRV
poisoning should be treated as kerosene poisoning with
supportive and symptomatic management and recommend that use
of household LMRV should be recognized and listed as a risk
factor in the etiology of kerosene poisoning.
References
1. Panwar M, Usha G, Kumath M. Status
epilepticus: an association with pyrethroid poisoning.
Indian J Crit Care Med. 2013;17:119-20.
2. Bhaskar EM, Moorthy S, Ganeshwala G,
Abraham G. Cardiac conduction disturbance due to prallethrin
(pyrethroid) poisoning. J Med Toxicol. 2010;6:27-30.
3. Tomlin C. A World Compendium. The
Pesticide Manual. Incorporating the Agrochemicals Handbook.
10th edition, 1994.. Bungay, Suffolk, UK: Crop Protection
Publications.
|
|
 |
|