Table IV Hematological, Serum Immunoglobulins Data and Total Number of Lymphocytes and T-Lymphocyte Subsets in Classical PKU Children with Different Plasm PA Concentrations and in BH4 Metabolism Disorders1 and comparison with the reference values (17,20-26)
|
|
Classical PKU |
P |
Classical PKU |
P |
BH4 metablism disorders |
P |
|||
|
|
Group I |
Reference |
Group II |
Reference |
Group II |
Reference |
|||
Hemoglobin (g/dL) |
11.8(9-13.7) |
12.4(10.5-16) |
0.043 |
11.75(10.4-13) |
12(10.5-14) |
0.514 |
11.8(9-16.3) |
12(10.5-14) |
0.519 |
Hematocrit (%) |
35.1(27-41.2) |
38.5(33-44) |
0.049 |
34.7(30.2-38) |
36.5(32-42) |
0.203 |
34.6(29.3-57) |
36(33-41) |
0.478 |
Iron (µg/dL) |
42(9-119) |
163(65-240) |
0.000 |
68(9-96) |
165(67-221) |
0.000 |
18(9-113) |
169(71-220) |
0.000 |
Copper (µg/dL) |
115(40-238) |
115(75-145) |
0.811 |
122(42-323) |
113(75-145) |
0.671 |
123(58-173) |
111(75-145) |
0.438 |
Zinc (µg/dL) |
57(30-134) |
103(76-134) |
0.000 |
85(60-100) |
102(76-134) |
0.003 |
69(27-92) |
103(76-134) |
0.000 |
Selenium (µg/dL) |
59(41-117) |
55(33-125) |
0.450 |
68(48-101) |
55(33-125) |
0.068 |
64(54-80) |
55(33-125) |
0.217 |
Ig G (mg/dL) |
840(450-2070) |
1160(304-2134) |
0.014 |
955(720-1620) |
1050(304-2134) |
0.671 |
790(490-1370) |
1035(304-2134) |
0.088 |
Ig M(mg/dL) |
96(40-313) |
144(32-484) |
0.028 |
90(41-163) |
124(32-392) |
0.052 |
115(63-412) |
124(32-484) |
0.748 |
Ig A(mg/dL) |
127(32-317) |
135(7-484) |
0.481 |
112(38-399) |
74(7-390) |
0.242 |
93(30-376) |
103(7-465) |
0.797 |
Total lymph. (109/L) |
4.1(1.65-11.4) |
3.2(1-11.9) |
0.080 |
5.6(1.53-12.33) |
4(1.1-11.9) |
0.379 |
6.5(2.0-11.5) |
3.2(1.1-11.9) |
0.008 |
CD3 Lymphocyte% |
0.72(0.56-0.79) |
0.66(0.39-0.83) |
0.140 |
0.68(0.54-0.78) |
0.65(0.39-0.78) |
0.378 |
0.69(0.53-0.76) |
0.65(0.39-0.78) |
0.193 |
109/L |
2.55(1.3-4.2) |
2.3(0.7-8) |
0.392 |
2.57(0.78-3.34) |
2.5(0.7-8) |
0.514 |
2.69(1.77-5.12) |
2.30(0.7-8) |
0.365 |
CD4 Lymphocyte% |
0.37(0.27-0.53) |
0.41(0.23-0.58) |
0.450 |
0.39(0.24-0.52) |
0.38(0.23-0.58) |
0.755 |
0.36(0.31-0.49) |
0.37(0.23-0.58) |
0.748 |
109/L |
1.39(0.64-2.9) |
1.30(0.3-5.5) |
0.900 |
1.44(0.54-2.2) |
1.5(0.3-5.5) |
0.378 |
1.48(0.8-2.61) |
1.3(0.3-5.5) |
0.478 |
CD8 Lymphocyte% |
0.27(0.19-0.49) |
0.25(0.09-0.39) |
0.185 |
0.24(0.15-0.41) |
0.23(0.11-0.34) |
0.551 |
0.27(0.18-0.36) |
0.23(0.09-0.35) |
0.519 |
109/L |
1.03(0.49-1.65) |
0.9(0.2-2.3) |
0.178 |
0.89(0.22-1.77) |
1(0.3-2.3) |
0.443 |
0.97(0.87-2.41) |
0.8(0.2-2.3) |
0.217 |
CD19 Lymphocyte% |
0.15(0.06-0.36) |
0.20(0.06-0.44) |
0.338 |
0.19(0.12-0.30) |
0.23(0.10-0.44) |
0.291 |
0.19(0.11-0.21) |
0.21(0.08-0.44) |
0.270 |
109/L |
0.50(0.18-2.08) |
0.6(0.1-3.1) |
0.615 |
0.83(0.14-1.11) |
0.9(0.2-3.1) |
0.378 |
0.71(0.29-1.12) |
0.7(0.2-3.1) |
0.898 |
CD16/56 Lymphoctye% |
0.10(0.02-0.24) |
0.12(0.02-0.31) |
0.257 |
0.13(0.06-0.16) |
0.08(0.02.26) |
0.143 |
0.10(0.05-0.25) |
0.09(0.02-0.27) |
0.478 |
109/L |
0.36(0.09-0.66) |
0.3(0.07-1.4) |
0.801 |
0.45(0.07-0.83) |
0.35(0.09-1.4) |
0.799 |
0.41(0.22-0.85) |
0.3(0.07-1.4) |
0.243 |
CD4/CD8 ratio |
1.34(0.55-2.68) |
NA |
NA |
1.43(0.68-2.94) |
NA |
NA |
1.24(0.9-2.69) |
NA |
NA |
CD4(%)/CD8(%) ratio |
1.34(0.54-2.54) |
1.8(0.9-3.9) |
0.078 |
1.41(0.59-2.78) |
1.65(0.9-3.9) |
0.713 |
1.45(0.94-2.68) |
1.6(0.9-3.9) |
0.797 |
1: Data represents Median (Range for study groups, +/– 2SD for reference values), NA: not amenable.