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Indian Pediatrics 1999;36: 1071-1072

Global Update


News in Brief

Controversy

Monkey business: In a moment of righteous indignation when activists of animal rights bodies and the Animal Welfare Board released 34 monkeys from a laboratory of the National Institute of Nutrition in Hyderabad, little did they know what was in store for them. Shantha Biotech who had sponsored the research on alpha Interferon has slapped a legal suit demanding a billion rupees, on the activists and the Government of India. Today Interferon alpha is beyond the reach of most Indian pockets. The impetuous act of the animal lovers has delayed animal toxicity trials by more than a year. The drug would have cut costs to 20% of the currently priced global brands. The court has issued a stay on further intereference with the animal trials. (Lancet 4 September 99).

Policy

Banning British Blood: The million-dollar question today is whether the JC virus is transmitted via blood transfusion. Nobody knows and nobody wants to take a chance. Countries around the world including the USA, Canada and Japan have banned the use of blood donated by people who have resided for more than 6 months in the UK. Envisaging a shortfall in blood donations the farsighted Canadians have already launched an ad campaign to increase donations (Lancet 4 September 99).

Virus Watch

Original sin: A horrifying hypothesis has resurfaced that polio vaccine trials on millions of Africans in the late 1950's may have resulted in the current HIV pandemic. It is widely  accepted that the HIV I virus has originated from a chimpanzee virus. How it jumped species is still hotly debated. A new deeply researched book called `The River' by Edward Hooper suggests that some of the vaccines were cultured on chimp kidney cells, which may have been the beginning. The geographic site where the first cases of HIV were documented and the vaccine trial areas coincide. But it doesn't explain how HIV 2, which is thought to have come from the sooty mangabey, jumped species. Though not all the ends tie up neatly, it casts a big shadow on vaccines cultured on animal tissue cultures (New Scientist 4 September 99).

Disease Watch

Two is too much: Two people in New York died of St. Louis Encephalitis in August and the city was sprayed aerially using helicopters; 150,000 leaflets and 17,000 cans of insect repellents were distributed and encephalitis surveillance, mosquito trapping and arbo virus testing was started on a war footing. Several more cases are being investigated and migratory birds are suspected to have introduced the virus into New York. The remarkable energy and thoroughness of the American people never ceases to amaze (Lancet 11 September 99).

Law

The case of the reluctant mother: The law has intervened in the case of the HIV infected mother who was not allowing her child to be tested and was continuing breast feeding against doctors orders. The court has ordered that the child be tested but interestingly says that "it cannot come between the baby and the breast". Though this case has evoked wide media interest, there have been a few cases earlier where the court has intervened when parents decisions have not been in the child's interests medically such as with Jehovah's Witnesses who do not allow blood transfusion. A child's right is not subsumed within the parent's rights however tiny it may be (BMJ 11 September 99).

Education

Literally speaking: By the turn of the century, the National Literacy Mission's zealous efforts with total literacy campaigns will have created around 325 million neo literates. But neoliterates are in perpetual danger of slipping back into illiteracy due to lack of practice. In a stroke of genius, a simple fun way to continue lifelong literacy called SLS was discovered. This stands for Same Language Subtitling of   film songs. In experiments on school children, those who watched subtitled song programs showed better reading ability than those who did not. Subtitled words change color to match the audio. It is already a reality in Gujarat with wide acceptance from viewers. In the Hindi belt, SLS of one episode of Chitrahaar would give reading practice to over 3 crore neoliterates at a cost of 3 paise/person/annum (Economic Times 18 September 99).

Gouri Rao Passi,
Associate Consultant,
Department of Pediatrics,
Choitham Hospital and Research Center,
Indore 452001, India.
E-mail: passi@vsnl.com

Indian Pediatrics 1999;36: 1072-1073

Pedscapes

Journal of Perinatal Medicine - www.degruyter.de/journals/jpm/index.html . This is the official journal of the world association of perinatal medicine. This bimonthly journal covers the field of neonatology and perinatal medicine. While the abstracts from this journal are available online to non subscribers, full text is accessible to subscribers. All the back issues of this journal from its date of first publication in Jan 1997 are available online.

Atlas of Medical Genetics - http://medgen.genetics.utah.edu/. This is an online atlas of various genetic disorders. The images are well classified into various groups. There is a thumbnail (small size image) of each disorder which on selection link to full size  images. The speed of access is quite fast considering the image content. Another feature here is a collection of MCQ's on Medical Genetics.

Safe Kids - www.safekids.org/. Safe kids is an organization which promotes child safety at home and aims to decrease morbidity due to accidents at home. The activities and campaigns of this organization and tips for measures for preventing accidents at home are listed in this site. An interesting feature is a child safety checklist, which when completed online, gives an assessment of risk of accident at home.

History of Perinatal Medicine - http://hippocrates.ouhsc.edu/Toubas/index.html . The history of neonatal and perinatal medicine with biographies and works of pioneers in the field was been well brought out in this site. The documents presented date back to the period from 1840-1910 with some documents translated from French. The works of Pierre Budin and Madame Henry, the first neonatologists, and Dr. Tarnier and Mr. Lion who designed the first incubators are presented here.

TB Bug Stops Here! - www.lupingroup.com. This is an exhaustive source of information on tuberculosis. Among the features are a monthly summary of abstracts from medline on latest research on TB, extensive reviews on various aspects of tuberculosis including DOTS, national consensus statement on multidrug resistant tuberculosis, multimedia tutorials, diagnostic dilemmas, discussion groups and statistical figures about tuberculosis in India.

National Institute of Allergy and Infectious Disease (NIH - USA) - www.niaid.nih.gov/default.htm#top .T he NIAID, a part of the National Institutes of Health, is involved in research on allergy and infectious diseases. Their website contains information on various infectious diseases including AIDS, Tuberculosis, Emerging Infections, Vaccine Research, Malaria, Hepatitis and Allergic Diseases like Asthma are presented here. These include a weekly feature on recent advances in various diseases and fact sheets on the various diseases.

Malaria Database - www.wehi.edu.au/MalDB-www/who.html. This is an information resource for scientists working in malaria research. It contains a wide variety of informations ranging from malarial DNA genome sequences to research jobs. The main thrust is on areas of research on the genetics of malarial parasite and vaccine development. A malaria discussion group and links to various resources on malaria are among the other features of this site.

Evidence Based Pediatrics - www.ped.med.umich.edu/ebm/. This site, from the University of Michigan, contains a critical evidence based appraisal of more than fifty controversial topics. The findings of these studies are summarized and presented well. There is a teaching module on conducting evidence-based studies.

Indian Journal of Gastroenterology - http://indianjgastro.com/. This is one of the few Indian medical journals to go online. The full text of the editorial and abstracts of articles of this quarterly journal are available online. There are quite a few articles of pediatric interest in this journal. The website is well designed with a fast access. All abstracts since 1982 will be available online in the near future, according to the publishers.

Note: The sites have been verified as on 25 Sept., 99. However, with the web being a dynamic medium, the URL's may change. The URL's can be checked in electronic version in case of any problems.

C. Vidyashankar,
Department of Pediatrics,
Base Hospital, Delhi Cantonment,
Delhi-110 010, India
E-mail: vidyashankarc@hotmail.com

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