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Recommendations

Indian Pediatrics 2000;37: 1083-1084

Japanese Encephalitis Vaccine


Immunization Committee of IAP

Preamble

Many States in India are endemic for Japanese Encephalitis (JE). Annual seasonal outbreaks occur is some districts of Tamil Nadu, Karnataka and Andhra Pradesh. In other districts of these States and in others in Maharashtra, West Bengal, Assam, North Eastern States, Uttar Pradesh, Orissa, Bihar and Haryana, JE occurs as periodic outbreaks at varying intervals.  The Central Research Institute (CRI) at Kasauli has the know-how to manufacture the inactivated JE vaccine. Earlier, CRI had been manufacturing about 2 million doses annually, and distributing it to the JE affected States. However, some States have defaulted in reimbursing the cost. In the public sector health care and public health system, there is poor demand, or none at all, for the vaccine. For these and other reasons, the production had been discontinued for a few years, but happily resumed in the current year. At present the production volume is about half a million doses.

 Under these circumstances, the Immuniza-tion Committee of the Indian Academy of Pediatrics recommends to the Government of India, the following steps.

  1. The Government may make the JE vaccine available to the private sector health care agencies through appropriate mechanisms on payment basis.

  2. The Government may call together, at an early date, a meeting of the State Health leadership of the JE affected States, experts from Indian Council of Medical Research (ICMR), IAP and other relevant agencies in order to design an immunization strategy in the districts with outbreaks of JE.

  3. The State Governments may develop District maps of JE infection burden using both clinical and laboratory criteria, using the help of other relevant and other interested agencies including local medical colleges. Such maps may be revised at intervals of 3-5 years.

  4. The recommended immunization schedule is to give, intramuscularly, 2 doses one month apart and a third dose 6-12 months after the second, provided the last dose precedes the anticipated seasonal increase in incidence. Immunization may com-mence from 24 months of age to 5 years. Children from rural areas and urban slums where humans and amplifier hosts (e.g., pigs) live in close contact are at a higher risk and may be given priority for vaccination.

  5. Wherever vaccination is planned or initiated, vector control measures must also be undertaken, especially by way of the control of breeding.

These recommendations are provisional and to be revised by the proposed strategy planning meeting. No recommendation for booster dose is being made now, pending the outcome of the meeting.

 Members of the IAP Committee on Immunization:

Chairperson: T. Jacob John

Convener: Anand P. Dubey

Members:
Thomas Cherian, Tapan Kumar Ghosh, Indrashekhar Rao, H.P.S. Sachdev and Navin Thacker.

Ex-officio Members:
Swati Y. Bhave, A. Parthasarathy, G.S. Hathi and Raju C. Shah.

Correspondence to
: Dr. A.P. Dubey, Convener, IAP Committee on Immunization, Professor of Pediatrics, Maulana Azad Medical College, New Delhi 110 002.

E-mail: [email protected]

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