Letters to the Editor Indian Pediatrics 1999; 36:324 |
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Nimesulide Toxicity |
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Another side-effect noted was periorbital oedema. Six children had this problem and it was mainly on the lower eyelids. It appeared within 12-24 hours of giving the drug. No other drugs were given and all renal parameters were normal in all children. The symptoms disappeared within 24 hours once the drug was discontinued. A similar finding has been reported earlier(3).
T.M. Anandakesavan, IVGM Hospital, Chalakudy, Thrissur 680 307, Kerala, India.
1. Goyal PK, Chandra J, Unnikrishnan G, Kumar S, Passah M. Double-blind randomized comparative evaluation of Nimesulide and Paracetamol as antipyretics. Indian Pediatr 1998; 35: 519-522. 2. Steinhauslin F, Munafo A, Buchn T, Macciochi A, Biollazl Renal effects of Nimesulide in Furosemide treated patients. Drugs 1993,46 (Supple 1): 257-262.
3. Nagabushana S. Nimesulide therapy. lAP J Pract Pediatr 1997; 5:
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