There are certain comments regarding a recent article regarding Melioidiosis [1]. Burkholderia Pseudomallei has been described as a Vietnamese time bomb’ý and is considered as a potential biological weapon. Despite disputes regarding the etiology of Plague in Maharashtra and Gujarat in 1994, the likely etiology was B. pseudomallei [2]. We have reported around 20 cases in a span of 4 years. Most of the published data on Melioidiosis comes from the coastal areas mainly Kerala, Karnataka, Maharashtra and Pondicherry [3-5] and most of the patients were diabetics. The infection is usually seen during the mmelioidiosis, prophylactic ceftazidime is advisable for the treatment as the infection may lead to septicemia and may have bad prognosis. In the laboratory, bipolar, gram negative bacilli should arouse the suspicion of B. Pseudomallei. Wrinkled, pinkish colonies on McConkey’s agar which are oxidase positive should be tested for gentamicin, and polymyxin B, as the bacilli is resistant to both.